The Adsorber
The CytoSorb adsorber is a CE-marked Class IIb medical device that is specifically approved for the removal of cytokines, bilirubin and myoglobin. Next to this CytoSorb is indicated for use intraoperatively during cardio-pulmonary bypass surgery for the removal of P2Y12-Inhibitor Ticagrelor and/or Factor Xa-Inhibitor. It is approved for use with standard hemodialysis-, hemofiltration-, ECMO- and heart lung-machines found in hospitals worldwide. CytoSorb comprises of several important features: An advanced biocompatible and hemocompatible porous polymer sorbent bead technology with extremely high binding capacity, documented ability to help to reduce a broad range of cytokines and other inflammatory mediators, bilirubin and myoglobin, and has good safety data in thousands of human treatments. In regards to cytokine removal, the goal is to reduce cytokines to levels that are no longer toxic, while still keeping the immune system intact. The content of the CytoSorb cartridge consists of a highly porous high-tech polymer. The tiny beads can bind to a wide range of inflammatory mediators such as e. g. cytokines, chemokines, and anaphylline toxins by virtue of their structure.